Detalhe da pesquisa
1.
Pharmacology of Small- and Intermediate-Conductance Calcium-Activated Potassium Channels.
Annu Rev Pharmacol Toxicol
; 60: 219-240, 2020 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31337271
2.
The shortcoming of using glibenclamide in exploratory clinical headache provocation studies.
Cephalalgia
; 43(12): 3331024231219475, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38064318
3.
Retroviral glycoprotein-mediated immune suppression via the potassium channel KCa3.1 - A new strategy for amelioration of inflammatory bowel diseases.
Clin Immunol
; 242: 109081, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35905828
4.
Quantification of the functional expression of the Ca2+ -activated K+ channel KCa 3.1 on microglia from adult human neocortical tissue.
Glia
; 64(12): 2065-2078, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27470924
5.
NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions.
J Pharmacol Exp Ther
; 350(3): 520-30, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24951278
6.
Pharmacological Profiling of KATP Channel Modulators: An Outlook for New Treatment Opportunities for Migraine.
Pharmaceuticals (Basel)
; 16(2)2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37259373
7.
Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype.
Mol Pharmacol
; 81(2): 210-9, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22046005
8.
Negative gating modulation by (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) depends on residues in the inner pore vestibule: pharmacological evidence of deep-pore gating of K(Ca)2 channels.
Mol Pharmacol
; 79(6): 899-909, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21363929
9.
Pharmacological modulation of the gating properties of small conductance Ca2+-activated K+ channels alters the firing pattern of dopamine neurons in vivo.
J Neurophysiol
; 104(3): 1726-35, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20660424
10.
Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers.
Basic Clin Pharmacol Toxicol
; 127(4): 329-337, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32628359
11.
Characterization of AN6001, a positive allosteric modulator of α6ß2-containing nicotinic acetylcholine receptors.
Biochem Pharmacol
; 174: 113788, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31887290
12.
Characterization of AN317, a novel selective agonist of α6ß2-containing nicotinic acetylcholine receptors.
Biochem Pharmacol
; 174: 113786, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31887288
13.
Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment.
Mol Pharmacol
; 76(3): 569-78, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19515965
14.
Tuning the excitability of midbrain dopamine neurons by modulating the Ca2+ sensitivity of SK channels.
Eur J Neurosci
; 29(9): 1883-95, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19473240
15.
Antibodies and venom peptides: new modalities for ion channels.
Nat Rev Drug Discov
; 18(5): 339-357, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728472
16.
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.
Theranostics
; 8(19): 5400-5418, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30555554
17.
Potassium channel expression and function in microglia: Plasticity and possible species variations.
Channels (Austin)
; 11(4): 305-315, 2017 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28277939
18.
Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime).
Biochim Biophys Acta
; 1665(1-2): 1-5, 2004 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15471565
19.
Pharmacological gating modulation of small- and intermediate-conductance Ca(2+)-activated K(+) channels (KCa2.x and KCa3.1).
Channels (Austin)
; 9(6): 336-43, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26217968
20.
The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation.
J Bone Miner Res
; 19(7): 1144-53, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15176998